ScienceDaily (May 6, 2010) — How much do we, who are alive today, differ from our most recent evolutionary ancestors, the cave-dwelling Neandertals, hominids who lived in Europe and parts of Asia and went extinct about 30,000 years ago? And how much do Neandertals, in turn, have in common with the ape-ancestors from which we are both descended, the chimpanzees?
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"The astonishing implication of the work we've just published," says Prof. Gregory Hannon, Ph.D., of Cold Spring Harbor Laboratory (CSHL), "is that we are incredibly similar to Neandertals at the level of the proteome, which is the full set of proteins that our genes encode."
Collaboration with a paleogenetics pioneer
Hannon, who is also an Investigator of the Howard Hughes Medical Institute and is well known for his work on small RNAs and RNA interference, was invited this past year to help examine Neandertal DNA by Dr. Svante Pääbo, a pioneer in paleogenetics, a field that employs genome science to study early humans and other Paleolithic-era creatures. In a separate paper, Pääbo's team today publishes in the same issue ofScience the first complete genome sequence for Neandertal, an achievement that builds on work he has led since 2006 at the Max Planck Institute for Evolutionary Genomics in Leipzig.
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