Perguntar de novo: crise epistêmica em genômica implica em quê para a teoria da evolução???

Curr Genomics. 2008 April; 9(2): 69–79.
doi: 10.2174/138920208784139546.
PMCID: PMC2674806
Copyright ©2008 Bentham Science Publishers Ltd.

On the Epistemological Crisis in Genomics
Edward R Dougherty*

Department of Electrical and Computer Engineering, Texas A&M University, Computational Biology Division, Translational Genomics Research Institute, USA
*Address correspondence to this author at the Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843-3128, USA; E-mail:edward@ece.tamu.edu

Received February 18, 2008; Revised March 7, 2008; Accepted March 8, 2008.
This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/) which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

There is an epistemological crisis in genomics. At issue is what constitutes scientific knowledge in genomic science, or systems biology in general. Does this crisis require a new perspective on knowledge heretofore absent from science or is it merely a matter of interpreting new scientific developments in an existing epistemological framework? This paper discusses the manner in which the experimental method, as developed and understood over recent centuries, leads naturally to a scientific epistemology grounded in an experimental-mathematical duality. It places genomics into this epistemological framework and examines the current situation in genomics. Meaning and the constitution of scientific knowledge are key concerns for genomics, and the nature of the epistemological crisis in genomics depends on how these are understood.

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