Constructing Partial Models of Cells
Norikazu Ichihashi1, Tomoaki Matsuura1, Hiroshi Kita2, Takeshi Sunami2, Hiroaki Suzuki1 and Tetsuya Yomo1,2,3
Author Affiliations
1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, Osaka, Japan
2Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST), Japan
3Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan
Correspondence: yomo@ist.osaka-u.ac.jp
Abstract
Understanding the origin of life requires knowledge not only of the origin of biological molecules such as amino acids, nucleotides and their polymers, but also the manner in which those molecules are integrated into the organized systems that characterize cellular life. In this article, we introduce a constructive approach to understand how biological molecules can be arranged to achieve a higher-order biological function: replication of genetic information.
Copyright © 2010 Cold Spring Harbor Laboratory Press; all rights reserved
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