© 2009 by The University of Chicago. All rights reserved. 0033‐5770/2009/8402‐0001$15.00
0033-5770/2009/8402-0001
DOI: 10.1086/598822
Transgenerational Epigenetic Inheritance: Prevalence, Mechanisms, and Implications for the Study of Heredity and Evolution
Eva Jablonka
The Cohn Institute for the History and Philosophy of Science and Ideas, Tel‐Aviv University, Tel‐Aviv 69978, Israeljablonka@post.tau.ac.il
Gal Raz
The Graduate School of Medicine, Tel‐Aviv University, Tel‐Aviv 69978, Israelgalraz@post.tau.ac.il
ABSTRACT
This review describes new developments in the study of transgenerational epigenetic inheritance, a component of epigenetics. We start by examining the basic concepts of the field and the mechanisms that underlie epigenetic inheritance. We present a comprehensive review of transgenerational cellular epigenetic inheritance among different taxa in the form of a table, and discuss the data contained therein. The analysis of these data shows that epigenetic inheritance is ubiquitous and suggests lines of research that go beyond present approaches to the subject. We conclude by exploring some of the consequences of epigenetic inheritance for the study of evolution, while also pointing to the importance of recognizing and understanding epigenetic inheritance for practical and theoretical issues in biology.
This review describes new developments in the study of transgenerational epigenetic inheritance, a component of epigenetics. We start by examining the basic concepts of the field and the mechanisms that underlie epigenetic inheritance. We present a comprehensive review of transgenerational cellular epigenetic inheritance among different taxa in the form of a table, and discuss the data contained therein. The analysis of these data shows that epigenetic inheritance is ubiquitous and suggests lines of research that go beyond present approaches to the subject. We conclude by exploring some of the consequences of epigenetic inheritance for the study of evolution, while also pointing to the importance of recognizing and understanding epigenetic inheritance for practical and theoretical issues in biology.
KEYWORDS
cell memory epigenetics induced heritable variations Lamarckism microevolution macroevolution
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NOTA CAUSTICANTE DESTE BLOGGER:
Ué, Darwin não tinha de uma vez por todas desqualificado as hipóteses transformistas de Lamarck, mesmo sendo mais lamarckista do que o próprio Lamarck na sexta edição do Origem das espécies??? E os nossos livros didáticos de Biologia do ensino médio aprovados pelo MEC/SEMTEC/PNLEM não trombeteiam aos quatro cantos que a teoria da evolução através da seleção natural de Darwin é superior às especulações transformistas de Lamarck???
Gente, eu estou mais do que ansioso para ver como que será o arcabouço teórico da nova teoria geral da evolução -- a SÍNTESE EVOLUTIVA AMPLIADA, que não pode e nem deve ser selecionista, para desespero de Darwin, da Nomenklatura científica e da Galera dos meninos e meninas de Darwin.
Espectro de Lamarck rondando Down? Lamarck redivivus... Cruz, credo!!!
