60 anos do dogma central da biologia

terça-feira, setembro 19, 2017

60 years ago, Francis Crick changed the logic of biology

Matthew Cobb 

Published: September 18, 2017 https://doi.org/10.1371/journal.pbio.2003243


Abstract

In September 1957, Francis Crick gave a lecture in which he outlined key ideas about gene function, in particular what he called the central dogma. These ideas still frame how we understand life. This essay explores the concepts he developed in this influential lecture, including his prediction that we would study evolution by comparing sequences.

Citation: Cobb M (2017) 60 years ago, Francis Crick changed the logic of biology. PLoS Biol 15(9): e2003243.


Published: September 18, 2017

Copyright: © 2017 Matthew Cobb. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Funding: Cold Spring Harbor Laboratory Sydney Brenner Research Scholarship. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing interests: The authors have declared that no competing interests exist.

Provenance: Not commissioned; externally peer reviewed.

FREE PDF GRATIS: PLoS Biology