An Adenine Code for DNA: A Second Life for N6-Methyladenine
Holger Heyn, Manel Esteller
Published Online: April 30, 2015
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Published online: April 30, 2015
Summary
DNA N6-methyladenine (6mA) protects against restriction enzymes in bacteria. However, isolated reports have suggested additional activities and its presence in other organisms, such as unicellular eukaryotes. New data now find that 6mA may have a gene regulatory function in green alga, worm, and fly, suggesting m6A as a potential “epigenetic” mark.
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