Regulação gênica: um interruptor transcricional controla a meiose - mero acaso, fortuita necessidade ou design inteligente?

terça-feira, dezembro 12, 2017

Gene Regulation: A transcriptional switch controls meiosis

A Elizabeth Hildreth Karen M Arndt Is a corresponding author

University of Pittsburgh, United States

INSIGHT Oct 24, 2017

Transcriptional switching between two mRNA transcripts regulates the assembly of the kinetochore during meiosis.

Abstract

A key protein involved in the segregation of meiotic chromosomes is produced 'just in time' by the regulated expression of two mRNA isoforms.

FREE PDF GRATIS: eLIFE

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SEE/VIDE:

Two papers in eLife, Elçin Ünal, Folkert van Werven and colleagues at the University of California at Berkeley and the Francis Crick Institute report a transcriptional switch that controls the timing of a critical event in the development of the yeast Saccharomyces cerevisiae (Chen et al., 2017; Chia et al., 2017).