"Ever since the Evolutionary Synthesis of the 1930s and 1940s, some biologists have expressed doubt that the Synthetic Theory [the prevailing neo-Darwinian version of evolution], based principally on mutation, genetic variation, and natural selection, adequately accounts for macroevolution, or evolution above the species level."
Futuyma, D.J., Can modern evolutionary theory explain macroevolution?; in: Serrelli, E. and Gontier, N. (Eds.), Macroevolution: Explanation, Interpretation And Evidence, Springer International Publishing, Berlin, pp. 29–85, 2015