The Human Cell Atlas: Technical approaches and challenges
Chung-Chau Hon Jay W Shin Piero Carninci Michael JT Stubbington
Briefings in Functional Genomics, elx029, https://doi.org/10.1093/bfgp/elx029
Published: 28 October 2017
Abstract
The Human Cell Atlas is a large, international consortium that aims to identify and describe every cell type in the human body. The comprehensive cellular maps that arise from this ambitious effort have the potential to transform many aspects of fundamental biology and clinical practice. Here, we discuss the technical approaches that could be used today to generate such a resource and also the technical challenges that will be encountered.
Human Cell Atlas, single cell, RNA sequencing, bioinformatics
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