Darwin, o problema da forma biológica permanece sem solução, mano!

segunda-feira, agosto 17, 2020

 On the problem of biological form

Marta Linde-Medina 

Theory in Biosciences volume 139, pages299–308(2020)

Ver a imagem de origem



Embryonic development, which inspired the first theories of biological form, was eventually excluded from the conceptual framework of the Modern Synthesis as irrelevant. A major question during the last decades has centred on understanding whether new advances in developmental biology are compatible with the standard view or whether they compel a new theory. Here, I argue that the answer to this question depends on which concept of morphogenesis is held. Morphogenesis can be conceived as (1) a chemically driven or (2) a mechanically driven process. According to the first option, genetic regulatory networks drive morphogenesis. According to the second, morphogenesis results from an invariant tendency of embryonic tissues to restore changes in mechanical stress. While chemically driven morphogenesis allows an extension of the standard view, mechanically driven morphogenesis would deeply transform it. Which of these hypotheses has wider explanatory power is unknown. At present, the problem of biological form remains unsolved.

Subscription or payment needed/Requer assinatura ou pagamento: Theory in Biosciences