Tissue Engineering: Building a better model of the retina
Milica Radisic
University of Toronto, Canada
INSIGHT Oct 4, 2019
DOI: 10.7554/eLife.51183
Retina-on-a-chip combines the benefits of organoids and organ-on-a-chip engineering.
Each chip has a vascular-like compartment (red) which is separated from the four organoid compartments above by a porous membrane. Schematic diagram (right) showing the various layers of cells in the retinal organoid (top) and the retinal pigment epithelium cells (RPE; yellow).
Image credit: Achberger et al. (CC BY 4.0)
Abstract
Researchers have combined organ-on-a-chip engineering with the benefits of organoids to make improved models of the human retina.
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