Molecular Machines and Targeted Molecular Dynamics: DNA in Motion
Available online 12 January 2010.
Refers to: | | The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis Structure, Volume 18, Issue 1, 13 January 2010, Pages 83-93, Andrei A. Golosov, Joshua J. Warren, Lorena S. Beese, Martin Karplus |
In this issue of Structure, Golosov et al. present molecular dynamics simulations that illuminate the process of DNA translocation by an A-family DNA polymerase. Several distinct phases are identified that have not been visualized through crystallographic studies.
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