Movimento unidirecional em torno de ligações duplas em motores moleculares rotativos: buscando ideias no mero acaso, fortuita necessidade ou no design inteligente?

quinta-feira, maio 03, 2018

Molecular rotary motors: Unidirectional motion around double bonds

Diederik Roke, Sander J. Wezenberg, and Ben L. Feringa

PNAS April 30, 2018. 201712784; published ahead of print April 30, 2018.

Edited by J. Fraser Stoddart, Northwestern University, Evanston, IL, and approved April 6, 2018 (received for review January 17, 2018)


The field of synthetic molecular machines has quickly evolved in recent years, growing from a fundamental curiosity to a highly active field of chemistry. Many different applications are being explored in areas such as catalysis, self-assembled and nanostructured materials, and molecular electronics. Rotary molecular motors hold great promise for achieving dynamic control of molecular functions as well as for powering nanoscale devices. However, for these motors to reach their full potential, many challenges still need to be addressed. In this paper we focus on the design principles of rotary motors featuring a double-bond axle and discuss the major challenges that are ahead of us. Although great progress has been made, further design improvements, for example in terms of efficiency, energy input, and environmental adaptability, will be crucial to fully exploit the opportunities that these rotary motors offer.

molecular motor alkene molecular machine