Resultados contraditórios: Origens dos principais clades de Archaea não correspondem com aquisição de genes de bactérias

quinta-feira, maio 28, 2015

Contradictory Results

Origins of major archaeal clades do not correspond to gene acquisitions from bacteria

Mathieu Groussin, Bastien Boussau, Gergely Szöllősi, Laura Eme, Manolo Gouy, Céline Brochier-Armanet, Vincent Daubin

doi: http://dx.doi.org/10.1101/019851

Abstract

In a recent article, Nelson-Sathi et al. [NS] report that the origins of Major Archaeal Lineages [MAL] correspond to massive group-specific gene acquisitions via horizontal gene transfer (HGT) from bacteria (Nelson-Sathi et al., 2015, Nature 517(7532):77-80). If correct, this would have fundamental implications for the process of diversification in microbes. However, a re-examination of these data and results shows that the methodology used by NS systematically inflates the number of genes acquired at the root of each MAL, and incorrectly assumes bacterial origins for these genes. A re-analysis of their data with appropriate phylogenetic models accounting for the dynamics of gene gain and loss between lineages supports the continuous acquisition of genes over long periods in the evolution of Archaea.

Copyright 

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