Genetics and Molecular Biology, 31, 2, 389-395 (2008)
Copyright © 2008, Sociedade Brasileira de Genética
Soft inheritance: Challenging the Modern Synthesis
Eva Jablonka 1 and Marion J. Lamb 2
1 The Cohn Institute for the History and Philosophy of Science and Ideas, Tel-Aviv University, Tel-Aviv, Israel.
2 11 Fernwood, Clarence Road, London, United Kingdom
This paper presents some of the recent challenges to the Modern Synthesis of evolutionary theory, which has dominated evolutionary thinking for the last sixty years. The focus of the paper is the challenge of soft inheritance - the idea that variations that arise during development can be inherited. There is ample evidence showing that phenotypic variations that are independent of variations in DNA sequence, and targeted DNA changes that are guided by epigenetic control systems, are important sources of hereditary variation, and hence can contribute to evolutionary changes. Furthermore, under certain conditions, the mechanisms underlying epigenetic inheritance can also lead to saltational changes that reorganize the epigenome. These discoveries are clearly incompatible with the tenets of the Modern Synthesis, which denied any significant role for Lamarckian and saltational processes. In view of the data that support soft inheritance, as well as other challenges to the Modern Synthesis, it is concluded that that synthesis no longer offers a satisfactory theoretical framework for evolutionary biology.
Key words: epigenetic inheritance, hereditary variation, Lamarckism, macroevolution, microevolution.
Received: March 18, 2008; Accepted: March 19, 2008
NOTA DESTE BLOGGER:
A SBG - Sociedade Brasileira de Genética, que publicou recentemente o Manifesto - Ciência e Criacionismo, uma verdadeira "estudantanda", também publicou este artigo sobre a falência heurística da Síntese Evolutiva Moderna!
Traduzindo em miúdos - Darwin kaput no contexto de justificação teórica.