Ginástica dos chaperones moleculares

domingo, agosto 15, 2010

Gymnastics of Molecular Chaperones

Molecular Cell, Volume 39, Issue 3, 321-331, 13 August 2010
Copyright © 2010 Elsevier Inc. All rights reserved.
10.1016/j.molcel.2010.07.012

Authors

Matthias P. Mayer



Summary

Molecular chaperones assist folding processes and conformational changes in many proteins. In order to do so, they progress through complex conformational cycles themselves. In this review, I discuss the diverse conformational dynamics of the ATP-dependent chaperones of the Hsp60, Hsp70, Hsp90, and Hsp100 families.


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