Máquinas moleculares e dinâmica molecular direcionada: o DNA em movimento

Molecular Machines and Targeted Molecular Dynamics: DNA in Motion

Janice D. Pata^1, 2, and Joachim Jaeger^1, 2

¹ Wadsworth Center, New York State Department of Health, Albany, NY 12201-0509, USA

² Department of Biomedical Sciences, University at Albany, Albany, NY 12201-0509, USA

Available online 12 January 2010. 

Refers to:

The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis Structure, Volume 18, Issue 1, 13 January 2010, Pages 83-93,  Andrei A. Golosov, Joshua J. Warren, Lorena S. Beese, Martin Karplus

In this issue of Structure, Golosov et al. present molecular dynamics simulations that illuminate the process of DNA translocation by an A-family DNA polymerase. Several distinct phases are identified that have not been visualized through crystallographic studies.

+++++

Professores, pesquisadores e alunos de universidades públicas e privadas com acesso ao site CAPES/Periódicos podem ler gratuitamente este artigo da Structure e de mais 15.000 publicações científicas.