Engineering Static and Dynamic Control of Synthetic Pathways
1 Department of Electrical Engineering and Computer Science, University of California at Berkeley, Berkeley, CA 94720, USA
2 Departments of Chemical Engineering and Bioengineering, University of California at Berkeley, Berkeley, CA 94720, USA
3 Physical Bioscience Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
4 Synthetic Biology Engineering Research Center, Emeryville, CA 94608, USA
5 Joint Bio Energy Institute, Emeryville, CA 94608, USA
2 Departments of Chemical Engineering and Bioengineering, University of California at Berkeley, Berkeley, CA 94720, USA
3 Physical Bioscience Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
4 Synthetic Biology Engineering Research Center, Emeryville, CA 94608, USA
5 Joint Bio Energy Institute, Emeryville, CA 94608, USA
Summary
- Maximizing the production of a desired small molecule is one of the primary goals in metabolic engineering. Recent advances in the nascent field of synthetic biology have increased the predictability of small-molecule production in engineered cells growing under constant conditions. The next frontier is to create synthetic pathways that adapt to changing environments.
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